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Senior Scientist ASG

Date: 20-May-2022

Location: Oxford, GB

Company: oxfordbiom

Our employees are able to develop their careers in exciting new medical technologies, and so can you.

 

 

Oxford BioMedica’s Analytical Services Group supports the development of products through analytical testing to facilitate manufacturing and process development, ensuring appropriate quality controls and use of analytics.

 

 

We are currently recruiting for a Senior HPLC Scientist to join the team.  The purpose of this role is to work within a small team of Scientists responsible for ensuring that reported QC release and stability results are robust, accurate and scientifically sound

 

Your responsibilities in this role would be:

  • Transfer of new assays from ADG (Analytical Development Group) to ASG, ensuring that the assays are scientifically sound and fit-for-use in GMP
  • Developing, validating and conducting all UPLC/HPLC analytical methods
  • Responsible for the set up and maintenance of a HPLC laboratory area and HPLC equipment.
  • Responsible for the training and development of scientists in HPLC analysis
  • Responsible for ensuring compliance of the CDS (cheomatography data system) in conjunction with the Analytical Services Administrator
  • Implementation of updates to GMP assays used in ASG following development work or validation
  • Management of analytical spreadsheets required for the calculation of results
  • Management and justification of assay acceptance criteria
  • Support the management of in-house control materials, including qualification studies to ensure fit-for-use
  • Monitoring of assay performance and investigation of any observed trends
  • Contribute to and/or lead thorough and timely investigation of invalid assays
  • Contribute to and/or lead thorough and timely investigation of OOS, OOE and OOT events
  • Contribute to and/or lead trouble-shooting into HPLC related assay problems inhibiting the reporting of results
  • Communicate with clients regarding product related HPLC analytics

 

To be successful in this role, you will have the following skills and experience:

 

  • Minimum BSc Degree programme level (or equivalent) with relevant experience in UPLC/HPLC
  • Proven technical analytical experience with particular emphasis on HPLC and UPLC within a GMP environment.
  • Working knowledge of assay development and/or validation
  • Ability to assess assays prior to transfer to ensure they are robust and scientifically sound
  • Use critical thinking skills to identify and solve assay-related problems
  • Apply appropriate acceptance criteria to assays and test samples to ensure robust and consistent assay performance
  • Use scientific understanding of assays to suggest continuous improvement activities
  • Understanding of basic statistical techniques for data analysis
  • Strong working knowledge of Microsoft Excel
  • Consistently ensure GMP compliance in all areas of work.
  • Strong knowledge and experience of working within a GMP environment
  • Experience of working with lentiviral vectors an advantage
  • Experience in qPCR Molecular Biology and protein chemistry would be an advantage
  • Working knowledge of JMP and Minitab an advantage

 

 

 

Do you want to feel inspired every day? We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and team work, and so can you.

 

 

Collaborate. Contribute. Change lives

 

 

No agencies please