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Scientist/Senior Scientist, Platform Proteomics Group

Date: 16-Mar-2023

Location: Oxford, GB

Company: oxfordbiom

We are at the centre of the rapidly growing cell and gene therapy sector. We deliver life-changing therapies to patients, and so can you.


We are currently recruiting for a Scientist/Senior Scientist in Mass Spectrometry based Proteomics to carry out the development & application of Liquid Chromatography Mass Spectrometry (LCMS) based assays in Cell & Gene Therapy applications.


This will be a lab-based role in the Platform Proteomics Group (PPG) within the Platform Research Group (PRG). The PPG is a highly collaborative team and employs cutting-edge mass spectrometry to support research and development activities. This position will give you the experience of working with a state-of-the-art lab with the latest equipment in mass spectrometry.


Your responsibilities in this role would be:

  • Routine maintenance, operation and troubleshooting of LCMS platform.

  • Execution and development of new LCMS based assays.

  • Lead in qualification and validation of LCMS based assays for GMP. 

  • Independently manage daily research activities and support team members.

  • Ensure a high standard of record keeping and documentation of all work.

  • Presentation of scientific data at internal meetings.


To be successful in this role, you will have the following skills and experience:

  • A PhD in chemistry, biochemistry, cell biology or similar sciences with a strong interest in applying mass spectrometry in research.

  • Experience in applying LCMS for the identification and quantification of proteins in various types of samples.

  • Experience in label-based or label-free quantitative proteomics worfklows.

  • Hands-on experience in operating and troubleshooting LCMS.

  • Ability to undertake and drive projects to agreed timelines and adapt to changes in project priorities.

  • Ability to communicate promptly and effectively about project progress and any issues via team meetings and project meetings.

  • Ability to work independently and as part of a hard-working, motivated, and enthusiastic team.


In addition, knowledge and/or experience in the following areas is advantageous, but necessary training will be provided:

  • Experience of absolute quantitation using PRM/MRM methodology using Orbitrap or triple quadrupole mass spectrometry.

  • Experience in DIA and associated data analysis.

  • Experience in developing and validating LCMS based analytical assays.



About Us:


We are an innovative leading viral vector specialist focused on delivering life changing therapies to patients.

Our innovative solutions and proven expertise allow us and our customers, the biotech and biopharma industry, to deliver life-saving therapies to reach even more patients.

The success of cell and gene therapy products transforms outcomes for millions of people suffering from some of the world’s worst diseases and medical conditions.


We work together, motivated to make a difference, and so can you.



What’s in it for you:


  • Highly competitive reward packages

  • Wellbeing programmes

  • Development opportunities

  • A 35-hour working week

  • Welcoming, friendly, supportive colleagues

  • A diverse and inclusive working environment

  • Our values are: Deliver Innovation, Be Inspiring and Have Integrity

  • State of the art laboratory and manufacturing facilities


We want you to feel inspired every day. We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment and teamwork, and so can you.


Collaborate. Contribute. Change lives