Manager, Durham Facilities Operations

Join Us in Changing Lives

At OXB, our people are at the heart of everything we do. We’re on a mission to enable life-changing therapies to reach patients around the world—and we’re looking for passionate individuals who embody our core values every day: Responsible, Responsive, Resilient, and Respectful.

Following the expansion of our US footprint with the acquisition of a new commercial-scale viral vector facility in Durham, North Carolina we have some new opportunities to join us.

We’re currently recruiting for a Facilities Manager to join our Manufacturing Operations team. In this role, you will be responsible for overseeing all Facilities operations within an FDA-approved clinical cGMP manufacturing facility, playing a key part in advancing our mission and making a real difference.

Your responsibilities in this role would be:

• Oversee all facilities operations for the manufacturing site, including office, lab, and other production areas.
• Manage and develop the Facilities and Calibration teams, ensuring effective daily operations and growth opportunities.
• Prioritize and monitor work orders through the CMMS system to maintain compliance and efficiency.
• Assist in developing and implementing programs for maintenance, calibration, and operation of GMP equipment, utilities, and systems.
• Daily management of service contracts, external janitorial teams, and vendor relationships to support operations.
• Partner with Manufacturing, Engineering, and Quality leadership to ensure proper maintenance intervals, calibration rigor, and continuous process improvements.
• Oversee site security systems, and act as primary liaison for building and grounds issues.
• Assist in Managing the Facilities operations budget, providing input on cost optimization and resource planning.
• Drive a culture of collaboration, communication, and compliance as a key member of the operations leadership team.
• Manage a team of Facilities Technicians.

We are Looking For:

• High School Diploma and a minimum of 12 years of directly relevant experience, bachelor’s degree and a minimum of 8 years of direct experience in facility operations, with proven experience in clean utilities and facilities operations within a biotech/pharmaceutical environment, or equivalent years of proven direct experience required.
• Experience in operation of GMP clean utilities and manufacturing facilities support required.
• Minimum 3 years managing a team.
• Exceptional written and oral communication skills at individual, team, and at all organizational levels are essential.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the United States.

About Us:

OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 30 years of experience in viral vectors; the driving force behind the majority of gene therapies.

OXB collaborates with some of the world’s most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB’s world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods, and depth of regulatory expertise.

Why Join Us?

• 💸 Competitive total reward packages
• 🧘 Wellbeing programs that support your mental and physical health
• 🚀 Career development opportunities to help you grow and thrive
• 🤝 Supportive, inclusive, and collaborative culture
• 🧪 State-of-the-art labs and manufacturing facilities
• 🌍 A company that lives its values: Responsible, Responsive, Resilient,         Respect

We want you to feel inspired every day. At OXB, we’re future-focused and growing fast. We succeed together—through passion, commitment, and teamwork.

Ready to Make a Difference?