Senior Scientist, Analytical Development (Chemistry), US

We use science to save lives, and so can you.

We are looking to recruit a hands on highly talented Senior Scientist to manage the Analytical Development (AD) Chemistry team, providing onsite support and development for chemistry assays.

This onsite Bedford, MA based role is an exciting opportunity to join an experienced organization whose mission is to enable our clients to deliver life-changing therapies to patients.

Your responsibilities in the role will be:

• Lead and manage the Analytical Development Chemistry team responsible for installation of new equipment, assay development and the daily operation of HPLC, LC/MS, CE-SDS, SEC and AUC development operations.
• Working in close collaboration with the AD Chemistry team to support client projects serving as the analytical methods expert to client teams.
• Lead and support the transfer, qualification, and validation of GMP analytical methods including but not limited to LC/MS, HPLC, Capillary Electrophoresis, (CE-SDS), and AUC assays. 
• Ensure AD Chemistry team members write protocols and generate reports related to QC method transfer, qualification, and validation activities. 
• Provide training and supervision to junior scientists on assay development, instrumentation, and data interpretation.
• The supporting and monitoring of on-going analytical method performance (e.g., system suitability trending, costing for new client projects) to drive continued improvement and optimization of OXB’s analytical methods. 
• Assisting with data trending of assay controls and reference standards, as needed. 
• Lead and support analytical method troubleshooting, as needed. 
• Partnering with internal and cross-functional departments (e.g., QC and QA) to ensure on-time delivery of OXB US client projects. 

We are looking for:

• MS/PhD in Chemistry or related area.
• Over 10 years of related experience with LC/MS, HPLC, CE-SDS and AUC.
• A proven people manager with the ability to shape teams.
• Strong expertise in analytical HPLC and LC/MS method development and basic troubleshooting.
• Independently motivated, detail oriented and have a strong problem-solving ability. 
• Hands-on experience in method development, qualification, validation and/or transfer. 
• Knowledge of quality principles and GMP, ICH and GLP regulations. 
• Experience creating/revising/reviewing operational SOPs, technical documents, protocols, and reports. 
• Able to work effectively in a fast-paced environment.
• Excellent communication, technical, organizational, and interpersonal skills are essential. 
• Able to work effectively in a collaborative team environment where results are achieved through influence and the incorporation of multiple points of view.

About Us:

OXB is a quality and innovation-led viral vector CDMO (Contract Development and Manufacturing Organization) with a mission to enable its clients to deliver life-changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 25 years of experience in viral vectors; the driving force behind the majority of gene therapies.

OXB collaborates with some of the world’s most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus, and adenoviral vectors. Oxford Biomedica’s world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods, and depth of regulatory expertise.

What’s in it for you:

• Competitive reward packages
• Development opportunities
• Welcoming, friendly, supportive colleagues
• A diverse and inclusive working environment
• State of the art laboratory and manufacturing facilities

We want you to feel inspired every day. We’re future-focused and our business is growing rapidly. We succeed together through passion, commitment, and teamwork, and so can you.

At OXB (US) LLC we are committed to providing equal opportunity to all employees and applicants. Our policy is to recruit, hire, train, and reward employees for their individual abilities, achievements, and experience without regard to race, colour, religion, sexual orientation, age, national origin, disability, marital or military status.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the United States.

Collaborate. Contribute. Change lives